Last Updated on August 19, 2026
Introduction
Causes
Clinical Features
Presentation
• Altered mental status e.g. due to acute massive haemorrhagic stroke /
intracranial bleed
Intracranial bleed (ICB)
Symptoms
•
Headache
Worse on leaning forward / coughing
• Vomiting
Signs
•
Cushing
🔒Cushing's response Elevated BP + Bradycardia Glasgow Coma Scale (GCS) • Pupil constriction occurs first
Further reading: raised ICP
• Altered
GCS
Open: https://www.myhouseman.my/glasgow-coma-scale-gcs/
• Irritability
•
Pupil changes
• Pupil dilatation occurs later
Investigations
Imaging
CT brain
• Effacement of the ventricles, basal cisterns and other CSF spaces
• Loss of grey-white matter differentiation
• Brain herniation
Reference: Radiopedia
Management
Aims e.g. subdural haematoma may require craniotomy / Burr hole
• To reduce
ICP
• To treat
underlying causes
Immediate management
• Elevate head of bed to 30 – 40° Remember the formula CPP = MAP – ICP This causes cerebral vasoconstriction → ↓ICP
• If hypotension, to
correct hypotension
• If intubated,
hyperventilate
• Consider sedation, hypothermia
• Arrange for CT brain
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Reference: Oxford Handbook of Clinical Medicine 10th ED
Definitive management
• Depends on the underlying cause Burr hole = a surgically created hole to help relieve pressure on the brain when fluid, such as blood, builds up and starts to compress brain tissue Source of definition: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/burr-holes
• Refer Neurosurgery for craniotomy /
Burr