Introduction Dosage Oral Contraindications Adverse Effects Anticholinergic effects of Buscopan is generally mild and self-limited. Further Reading
Category: Medications
Adenosine– Underlying asthma Bactrim (Trimethoprim / Sulfamethoxazole)– Any G6PD deficiency? Labetalol / any beta blocker– Underlying asthma? SC Fondaparinux / SC Clexane– Underlying ESRF / advanced CKD? MDI Salbutamol– any hypokalaemia?– any severe tachycardia? IVI insulin– any hypokalaemia? Streptokinase– any recent thrombolysis? Paracetamol– how is the LFT? Any transaminitis? Penicillin– any allergy? Propofol– any (soybean) allergy?
Preparation Clinical Use Anti-ischemic / anti-angina. As ADD-ON therapy for the symptomatic treatment of patients with stable angina pectoris Mechanism of Action Trimetazidine prevents a decrease in intracellular ATP levels. This ensures proper functioning of ionic pumps and transmembrane sodium-potassium flow. Trimetazidine inhibits β-oxidation of fatty acids. This enhances glucose oxidation.Energy obtained during glucose oxidation […]
Introduction Indications Doses Hypertension Supraventricular tachycardia Contraindications Related Posts
Introduction A neuraminidase inhibitor Prevents new viral particles from being released by infected cells Indication H1N1 influenza Caution Hepatitis / Transaminitis Side Effects Nausea Vomiting Diarrhoea Headache Preparation Capsule (75 mg) Syrup (60 mg / 5 mL) Dosage H1N1 influenza • Duration: 5 days• OD dosing for prophylaxis• BD dosing for treatment Adult C Oseltamivir […]
Examples Subcutaneous injection Fondaparinux Oral Rivaroxaban Apixaban Adverse Effects Bleeding Easy bruising Related Posts Haemostasis
Mechanism of Action Slows transmission across AV node It has only little effect on other myocardial cells / conduction pathways Notes• Adenosine receptors are found in the lungs• Thus, adenosine can stimulate sensory nerve fibres in lungs to produce shortness of breath• Adenosine causes bronchoconstriction Indications supraventricular tachycardia Administration Preparation Make sure patient has a […]
Mechanism of Action Examples Clopidogrel (Plavix®) Ticagrelor (Brilinta®) Prasugel Related Posts
Introduction • Third generation beta-blocker, non-selective Advantages • Effective in hypertension• Improves mortality & morbidity in patients with heart failure• No adverse effect on insulin resistance & lipid metabolism Precaution • Safety in pregnancy not established Dosage Notes: different dosage for patients with heart failure / angina Hypertension • Starting dose: 12.5 mg OD• Recommended […]
Introduction • A non-selective beta-blocker• A class III anti-arrhythmic drug Mechanism of Action • It prolongs cardiac action potential and QT interval by delaying slow outward potassium ion current Adverse Effects • Long QT syndrome• Torsades de pointes Cautions • Requires close monitoring of renal profile (potassium level) Related Posts Beta-blockers