Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Criteria by Barrter and Schwartz Causes Related Posts Further Reading / Reference

Verapamil

Introduction Indications Doses Hypertension Supraventricular tachycardia Contraindications Related Posts

H1N1

Introduction A subtype of the 2009 pandemic High risk groups: Immunocompromised / chronic illness Pregnant women Children >5 years old Clinical Features Symptoms Fever Diarrhoea Vomiting Cough Sore throat Rhinitis Headache, myalgia, lethargy Investigation Influenza PCR Treatment Oseltamivir (Tamiflu®)

Oseltamivir (Tamiflu®)

Introduction A neuraminidase inhibitor Prevents new viral particles from being released by infected cells Indication H1N1 influenza Caution Hepatitis / Transaminitis Side Effects Nausea Vomiting Diarrhoea Headache Preparation Capsule (75 mg) Syrup (60 mg / 5 mL) Dosage H1N1 influenza • Duration: 5 days• OD dosing for prophylaxis• BD dosing for treatment Adult C Oseltamivir […]

Pleural Tap / Thoracentesis

Introduction =====– Can be done or Contraindications Equipment Landmarks Notes Drainage Investigations • The following investigations are sent in the same setting of pleural tapping• Pleural fluid will be classified as exudative or transudative, following Light’s criteria (i) Pleural fluid Usually, these are the common investigations sent for pleural fluid: (ii) Blood (iii) Imaging Related […]

Syndrome X

Introduction Also called microvascular angina Key features: positive findings on exercise stress test, but normal coronary artery angiography Clinical Features Symptoms Angina on exertion Investigations ECG at rest: normal Exercise stress test: ST depression Coronary arteries angiography: normal Treatment Nitrates

Factor Xa Inhibitors

Examples Subcutaneous injection Fondaparinux Oral Rivaroxaban Apixaban Adverse Effects Bleeding Easy bruising Related Posts Haemostasis

Adenosine

Mechanism of Action Slows transmission across AV node It has only little effect on other myocardial cells / conduction pathways Notes• Adenosine receptors are found in the lungs• Thus, adenosine can stimulate sensory nerve fibres in lungs to produce shortness of breath• Adenosine causes bronchoconstriction Indications supraventricular tachycardia Administration Preparation Make sure patient has a […]

P2Y12 receptor antagonists

Mechanism of Action Examples Clopidogrel (Plavix®) Ticagrelor (Brilinta®) Prasugel Related Posts

Aortic Regurgitation

Causes Valvular causes • Infective endocarditis• Rheumatic fever• Aortic root dilatation • Marfan’s syndrome• Ehler-Danlos syndrome• • Hypertension• Aortic dissection • Ankylosing spondylitis• Syphilis Clinical Features Symptoms • Shortness of breath• Signs • Wide pulse pressure• Collapsing pulse• Murmurs: Early diastolic murmur, Austin-Flint murmur (in severe AR) Investigations • Echocardiography Management Medical • Treatment of […]

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