Serum Osmolality / Osmolal Gap

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Last Updated on August 19, 2026

Table of Contents

    Table of Contents

    Introduction

    = measured serum osmolality – calculated serum osmolality
    • Calculated serum osmolality = 2[+] + +
    • Marked increased osmolal gap (>25 mOsm) is pathognomonic of toxic alcohol poisoning!

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    Table of Contents

    Index